Invasion kinetics of human endothelial cells by Toxoplasma gondii RH and ME49 strains
نویسندگان
چکیده
منابع مشابه
Synchronous invasion of host cells by Toxoplasma gondii.
Synchronous invasion of host cells by Toxoplasma gondii B.F.C. Kafsack a,∗, C. Beckers b, V.B. Carruthers a a W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205-1918, USA b Division of Geographic Medicine, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35...
متن کاملIdentification of potential apicoplast associated therapeutic targets in human and animal pathogen Toxoplasma gondii ME49
UNLABELLED Toxoplasma gondii ME49 is an obligatory intracellular apicomplexa parasite that causes toxoplasmosis in humans, domesticated and wild animals. Waterborne outbreaks of acute toxoplasmosis worldwide reinforce the transmission of Toxoplasma gondii ME49 to humans through contaminated water and may have a greater epidemiological impact than previously believed. In the quest for drug and v...
متن کاملConjugated Linoleic Acid Stimulates Apoptosis in RH and Tehran Strains of Toxoplasma gondii, in Vitro
BACKGROUND The aim of this study was to evaluate the effects of conjugated linoleic acid (CLA) on apoptosis of tachyzoites of T. gondii, RH strain (type I) and the cyst-forming Tehran strain (type II) in vitro. METHODS Toxoplasma strains were injected into the peritoneal cavity of BALB/c mice. The Tehran strain forms cysts in the brain of mice. Bradyzoites within the cysts are reactivated to ...
متن کاملAvirulent strains of Toxoplasma gondii infect macrophages by active invasion from the phagosome.
Unlike most intracellular pathogens that gain access into host cells through endocytic pathways, Toxoplasma gondii initiates infection at the cell surface by active penetration through a moving junction and subsequent formation of a parasitophorous vacuole. Here, we describe a noncanonical pathway for T. gondii infection of macrophages, in which parasites are initially internalized through phag...
متن کاملconjugated linoleic acid stimulates apoptosis in rh and tehran strains of toxoplasma gondii, in vitro.
background: the aim of this study was to evaluate the effects of conjugated lino-leic acid (cla) on apoptosis of tachyzoites of t . gondii , rh strain (type i) and the cyst-forming tehran strain (type ii) in vitro. methods: toxoplasma strains were injected into the peritoneal cavity of balb/c mice. the tehran strain forms cysts in the brain of mice. bradyzoites within the cysts are reactivated ...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2012
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2012.05.347